AMITIZA May Help
AMITIZA and Chronic Constipation
AMITIZA (24 mcg) twice daily is approved to treat Chronic Idiopathic Constipation in adults.
AMITIZA treats Chronic Constipation by increasing fluid secretions in the bowel, to help you to pass stool. In short, AMITIZA can help increase bowel movement frequency in people with Chronic Constipation.
AMITIZA May Help
Ask your healthcare provider about AMITIZA.
In two 4-week clinical studies, people taking AMITIZA averaged 5 to 6 bowel movements per week, versus 3 to 4 without AMITIZA.
A majority of people had a bowel movement within 24 hours.*
In two 4-week clinical studies, AMITIZA improved symptoms† of:
- straining
- stool consistency
- abdominal discomfort
- abdominal bloating
- constipation severity
Individual results may vary.
AMITIZA is not a laxative or fiber. It is a small oral gelcap that you take twice a day with food and water. AMITIZA should be swallowed whole, do not break apart or chew. Tell your doctor if you have liver problems.
Not sure how to talk with your healthcare provider about your Chronic Constipation? This section includes a Treatment Conversation Guide to help with that conversation. Here, you can answer questions about your symptoms and keep track of how they affect you. There's even an area where you can write down next steps. Just remember, the more information you give your healthcare provider, the more likely they will be able to help you. So come prepared to share.
Indication
AMITIZA (24 mcg) twice daily is approved to treat Chronic Idiopathic Constipation in adults. "Idiopathic" means the cause of the constipation is unknown and not due to an underlying illness or medication.
Important Safety Information
AMITIZA is not for everyone. If you know or suspect you have a bowel blockage, do not take AMITIZA. If you are unsure, your healthcare provider should evaluate your condition before starting AMITIZA. You should not take AMITIZA if you have severe diarrhea.
AMITIZA has not been studied in pregnant women and should only be used during a pregnancy if the potential benefits justify the potential risk to the fetus. Women should have a negative pregnancy test before beginning treatment with AMITIZA and need to practice effective birth control measures. If you are pregnant or become pregnant while being treated with AMITIZA, talk to your healthcare provider to evaluate the risks to the fetus.
Some patients taking AMITIZA may experience nausea or diarrhea. If nausea occurs, take AMITIZA with food. If your nausea or diarrhea becomes severe, tell your healthcare provider.
Within an hour of taking AMITIZA, a sensation of chest tightness and shortness of breath may occur. These symptoms usually go away within three hours, but may recur with repeated use. Tell your healthcare provider if you experience these symptoms.
The most common side effects of taking AMITIZA (24 mcg) twice daily, orange capsules for Chronic Idiopathic Constipation are nausea, diarrhea, and headache. These are not all the side effects associated with AMITIZA.
Tell your doctor if you have liver problems.








