What to Expect
What to Expect When Taking AMITIZA
Your healthcare provider has prescribed AMITIZA—a treatment that may help you find relief. Relief is defined as three or more spontaneous bowel movements per week.
In two 4-week clinical studies, people taking AMITIZA averaged 5 to 6 bowel movements per week, versus 3 to 4 without AMITIZA.
While everyone is different and individual results may vary, AMITIZA usually works within 24 hours. In two 4-week clinical studies, 57% to 63% of patients who received AMITIZA experienced a bowel movement within 24 hours after taking AMITIZA compared to 32% to 37% of patients who received a placebo.
In two 4-week clinical studies, AMITIZA improved symptoms of:
- straining
- stool consistency
- abdominal discomfort
- abdominal bloating
- constipation severity
Based on two 4-week clinical studies, AMITIZA improved symptoms of Chronic Constipation versus placebo, including abdominal bloating, abdominal discomfort, stool consistency, straining, and constipation severity.
Indication
AMITIZA (24 mcg) twice daily is approved to treat Chronic Idiopathic Constipation in adults. "Idiopathic" means the cause of the constipation is unknown and not due to an underlying illness or medication.
Important Safety Information
AMITIZA is not for everyone. If you know or suspect you have a bowel blockage, do not take AMITIZA. If you are unsure, your healthcare provider should evaluate your condition before starting AMITIZA. You should not take AMITIZA if you have severe diarrhea.
AMITIZA has not been studied in pregnant women and should only be used during a pregnancy if the potential benefits justify the potential risk to the fetus. Women should have a negative pregnancy test before beginning treatment with AMITIZA and need to practice effective birth control measures. If you are pregnant or become pregnant while being treated with AMITIZA, talk to your healthcare provider to evaluate the risks to the fetus.
Some patients taking AMITIZA may experience nausea or diarrhea. If nausea occurs, take AMITIZA with food. If your nausea or diarrhea becomes severe, tell your healthcare provider.
Within an hour of taking AMITIZA, a sensation of chest tightness and shortness of breath may occur. These symptoms usually go away within three hours, but may recur with repeated use. Tell your healthcare provider if you experience these symptoms.
The most common side effects of taking AMITIZA (24 mcg) twice daily, orange capsules for Chronic Idiopathic Constipation are nausea, diarrhea, and headache. These are not all the side effects associated with AMITIZA.
Tell your doctor if you have liver problems.
