For Healthcare Providers

How to Take AMITIZA

It's important to take AMITIZA as prescribed by your doctor, and for as long as they recommend. The suggested dosage for AMITIZA is 1 gelcap at breakfast and 1 at dinner, or as prescribed by your doctor. Swallow whole, do not break apart or chew. Also, remember to check in regularly with your doctor, so they can monitor your progress, and make adjustments as needed.

Using AMITIZA

Here are some important things to keep in mind when taking AMITIZA.

  • If you miss a dose of AMITIZA, do not take 2 capsules to make up for the missed dose. Instead, just wait until the next time you are supposed to take it, and take your normal dose.
  • Store AMITIZA at room temperature in a childproof container that is tightly closed and out of the reach of children.
  • Do not use AMITIZA past the expiration date shown on the package.
  • As you continue to take AMITIZA, use the AMITIZA Progress Checker to note your progress.

Indication

AMITIZA (24 mcg) twice daily is approved to treat Chronic Idiopathic Constipation in adults. "Idiopathic" means the cause of the constipation is unknown and not due to an underlying illness or medication.

Important Safety Information

AMITIZA is not for everyone. If you know or suspect you have a bowel blockage, do not take AMITIZA. If you are unsure, your healthcare provider should evaluate your condition before starting AMITIZA. You should not take AMITIZA if you have severe diarrhea.

AMITIZA has not been studied in pregnant women and should only be used during a pregnancy if the potential benefits justify the potential risk to the fetus. Women should have a negative pregnancy test before beginning treatment with AMITIZA and need to practice effective birth control measures. If you are pregnant or become pregnant while being treated with AMITIZA, talk to your healthcare provider to evaluate the risks to the fetus.

Some patients taking AMITIZA may experience nausea or diarrhea. If nausea occurs, take AMITIZA with food. If your nausea or diarrhea becomes severe, tell your healthcare provider.

Within an hour of taking AMITIZA, a sensation of chest tightness and shortness of breath may occur. These symptoms usually go away within three hours, but may recur with repeated use. Tell your healthcare provider if you experience these symptoms.

The most common side effects of taking AMITIZA (24 mcg) twice daily, orange capsules for Chronic Idiopathic Constipation are nausea, diarrhea, and headache. These are not all the side effects associated with AMITIZA.

Please click here for complete Prescribing Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.