Sticking to Your Treatments
Congratulations on discussing your condition with your healthcare provider and receiving your prescription for AMITIZA . You're on track to managing your condition and that's great. But your relationship with your healthcare provider doesn't stop there.
Because Chronic Idiopathic Constipation is a medical condition, you will need to stick to your treatments, monitor your progress, and regularly share that information with your healthcare provider.
Of course you intend to take your AMITIZA twice daily with food and water, just as your doctor prescribed. But should you accidentally miss a dose, just skip that dose. Do not take 2 capsules to make up for the missed dose. Just wait until the next time you are supposed to take it, and then take your normal dose. Tell your doctor if you have liver problems.
Stay on Track with Your Treatments
- It all starts with filling the prescription. You may be eligible for the AMITIZA Healthy Savings Program.
- Take AMITIZA as directed by your healthcare provider. For Chronic Constipation, the dose is 1 orange 24 mcg gelcap taken twice a day with food and water. Swallow the gelatin capsules whole. Do not break them apart or chew them. Tell your doctor if you have liver problems.
- Chart your progress. You have likely documented your constipation symptoms in the past. Use the Progress Checker now to show how you are doing on therapy.
- Schedule a follow-up appointment with your healthcare provider.
Indication
AMITIZA (24 mcg) twice daily is approved to treat Chronic Idiopathic Constipation in adults. "Idiopathic" means the cause of the constipation is unknown and not due to an underlying illness or medication.
Important Safety Information
AMITIZA is not for everyone. If you know or suspect you have a bowel blockage, do not take AMITIZA. If you are unsure, your healthcare provider should evaluate your condition before starting AMITIZA. You should not take AMITIZA if you have severe diarrhea.
AMITIZA has not been studied in pregnant women and should only be used during a pregnancy if the potential benefits justify the potential risk to the fetus. Women should have a negative pregnancy test before beginning treatment with AMITIZA and need to practice effective birth control measures. If you are pregnant or become pregnant while being treated with AMITIZA, talk to your healthcare provider to evaluate the risks to the fetus.
Some patients taking AMITIZA may experience nausea or diarrhea. If nausea occurs, take AMITIZA with food. If your nausea or diarrhea becomes severe, tell your healthcare provider.
Within an hour of taking AMITIZA, a sensation of chest tightness and shortness of breath may occur. These symptoms usually go away within three hours, but may recur with repeated use. Tell your healthcare provider if you experience these symptoms.
The most common side effects of taking AMITIZA (24 mcg) twice daily, orange capsules for Chronic Idiopathic Constipation are nausea, diarrhea, and headache. These are not all the side effects associated with AMITIZA.
Tell your doctor if you have liver problems.

