For Healthcare Providers

Learn More About Chronic Constipation

The Digestive Disease National Coalition (DDNC)

The Digestive Disease National Coalition (DDNC) is an advocacy organization comprised of the major national voluntary and professional societies concerned with digestive diseases. The DDNC focuses on improving public policy related to digestive diseases and increasing public awareness with respect to the many diseases of the digestive system. The DDNC was founded in 1978 and is based in Washington, D.C.

507 Capitol Court NE, Suite 200
Washington, DC 20002
Phone: 1-202-544-7497 Fax: 1-202-546-7105
www.ddnc.org

The Gastro-Intestinal Research Foundation (GIRF)

The Gastro-Intestinal Research Foundation (GIRF) is a not-for-profit organization dedicated to raising funds for clinical and laboratory research in digestive diseases in the Gastroenterology Section at the University of Chicago Medical Center.

70 East Lake Street, Suite 1015
Chicago, IL 60601-5907
Phone: 1-312-332-1350 Fax: 1-312-332-4757
www.girf.org

International Foundation for Functional Gastrointestinal Disorders (IFFGD) Inc.

The IFFGD is a nonprofit education and research organization dedicated to informing, assisting, and supporting people affected by gastrointestinal (GI) disorders. Founded in 1991, the IFFGD works with patients, families, physicians, nurses, practitioners, investigators, regulators, employers, and others to improve digestive health in adults and children.

PO Box 170864
Milwaukee, WI 53217-8076
Phone: 1-888-964-2001 or 1-414-964-1799 Fax: 1-414-964-7176
www.aboutconstipation.org

National Digestive Diseases Information Clearinghouse (NDDIC)

The NDDIC is an information dissemination service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The NIDDK is part of the National Institutes of Health (NIH), which is part of the U.S. Department of Health and Human Services.

NDDIC was established in 1980 to increase knowledge and understanding about digestive diseases among people with these conditions and their families, health care professionals, and the general public. To carry out this mission, NDDIC works closely with a coordinating panel of representatives from Federal agencies, voluntary organizations on the national level, and professional groups to identify and respond to informational needs about digestive diseases.

2 Information Way
Bethesda, MD 20892-3570
Phone: 1-800-891-5389 Fax: 1-703-738-4929
www.digestive.niddk.nih.gov

Indication

AMITIZA (24 mcg) twice daily is approved to treat Chronic Idiopathic Constipation in adults. "Idiopathic" means the cause of the constipation is unknown and not due to an underlying illness or medication.

Important Safety Information

AMITIZA is not for everyone. If you know or suspect you have a bowel blockage, do not take AMITIZA. If you are unsure, your healthcare provider should evaluate your condition before starting AMITIZA. You should not take AMITIZA if you have severe diarrhea.

AMITIZA has not been studied in pregnant women and should only be used during a pregnancy if the potential benefits justify the potential risk to the fetus. Women should have a negative pregnancy test before beginning treatment with AMITIZA and need to practice effective birth control measures. If you are pregnant or become pregnant while being treated with AMITIZA, talk to your healthcare provider to evaluate the risks to the fetus.

Some patients taking AMITIZA may experience nausea or diarrhea. If nausea occurs, take AMITIZA with food. If your nausea or diarrhea becomes severe, tell your healthcare provider.

Within an hour of taking AMITIZA, a sensation of chest tightness and shortness of breath may occur. These symptoms usually go away within three hours, but may recur with repeated use. Tell your healthcare provider if you experience these symptoms.

The most common side effects of taking AMITIZA (24 mcg) twice daily, orange capsules for Chronic Idiopathic Constipation are nausea, diarrhea, and headache. These are not all the side effects associated with AMITIZA.

Please click here for complete Prescribing Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.