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About IBS-C and AMITIZA

Understanding IBS with Constipation

Irritable Bowel Syndrome with Constipation (IBS-C) is more common than you think. Identify symptoms today.
Learn more about IBS with constipation

AMITIZA & IBS-C

AMITIZA (8 mcg) twice daily is a prescription medicine approved to relieve the overall symptoms of IBS-C in adult women (abdominal discomfort, abdominal pain, bowel habits, and other IBS symptoms).
Learn more about AMITIZA & IBS-C

AMITIZA May Help

Ask your doctor about AMITIZA.
Learn more about how AMITIZA may help

How AMITIZA Works

AMITIZA is a treatment for IBS-C in adult women.
Learn more about how AMITIZA works

AMITIZA Is Different

AMITIZA is not a laxative or fiber. Find out what makes AMITIZA different.
Learn more about how AMITIZA is different

Frequently Asked Questions

Have questions about AMITIZA?
Learn more in our FAQ section

Questionnaire

Think you may have IBS-C?
Try our questionnaire

Financial Help

At Takeda, we believe appropriate patients should have access to AMITIZA regardless of their financial situation. Find out which programs you may be eligible for.
Learn more in our Financial Help section

Links to Additional Resources

Looking for more information about IBS-C?
Learn more about additional resources

Indication

AMITIZA (lubiprostone) 8 mcg twice daily is approved to treat Irritable Bowel Syndrome with Constipation (IBS-C) in women 18 years of age and older.

Important Safety Information

AMITIZA (lubiprostone) is not for everyone. If you know or suspect you have a bowel blockage, do not take AMITIZA. If you are unsure, your healthcare provider should evaluate your condition before starting AMITIZA. You should not take AMITIZA if you have severe diarrhea.

Some patients taking AMITIZA may experience nausea or diarrhea. If nausea occurs, take AMITIZA with food. If your nausea or diarrhea becomes severe, tell your healthcare provider.

Within an hour of taking AMITIZA, a sensation of chest tightness and shortness of breath may occur. These symptoms usually go away within three hours, but may recur with repeated use. Tell your healthcare provider if you experience these symptoms.

The most common side effects of taking AMITIZA (8 mcg) twice daily, pink capsules for IBS-C are nausea, diarrhea, and abdominal pain. These are not all the side effects associated with AMITIZA.

AMITIZA has not been studied in pregnant women. Based on animal studies, AMITIZA may cause fetal harm. AMITIZA should only be used during pregnancy if the potential benefits justify the potential risk to the fetus. If you are pregnant or become pregnant while being treated with AMITIZA, talk to your healthcare provider to evaluate the risks to the fetus. Tell your doctor if you are nursing and monitor infants for diarrhea.

Tell your doctor if you have liver problems.

Please click here for complete Prescribing Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.