How AMITIZA Works
AMITIZA works by activating ClC-2 chloride channels in the intestine, promoting fluid secretion, and may aid in the passing of stool. The mechanism of action in Irritable Bowel Syndrome with Constipation (IBS-C) is not fully understood. AMITIZA is an FDA-approved prescription treatment for IBS-C in women 18 years of age and older. AMITIZA can help address the overall symptoms of IBS-C, which include abdominal discomfort, abdominal pain, bowel habits, and other IBS symptoms.
Ask your doctor about AMITIZA.
Indication
AMITIZA (lubiprostone) 8 mcg twice daily is approved to treat Irritable Bowel Syndrome with Constipation (IBS-C) in women 18 years of age and older.
Important Safety Information
AMITIZA (lubiprostone) is not for everyone. If you know or suspect you have a bowel blockage, do not take AMITIZA. If you are unsure, your healthcare provider should evaluate your condition before starting AMITIZA. You should not take AMITIZA if you have severe diarrhea.
Some patients taking AMITIZA may experience nausea or diarrhea. If nausea occurs, take AMITIZA with food. If your nausea or diarrhea becomes severe, tell your healthcare provider.
Within an hour of taking AMITIZA, a sensation of chest tightness and shortness of breath may occur. These symptoms usually go away within three hours, but may recur with repeated use. Tell your healthcare provider if you experience these symptoms.
The most common side effects of taking AMITIZA (8 mcg) twice daily, pink capsules for IBS-C are nausea, diarrhea, and abdominal pain. These are not all the side effects associated with AMITIZA.
AMITIZA has not been studied in pregnant women. Based on animal studies, AMITIZA may cause fetal harm. AMITIZA should only be used during pregnancy if the potential benefits justify the potential risk to the fetus. If you are pregnant or become pregnant while being treated with AMITIZA, talk to your healthcare provider to evaluate the risks to the fetus. Tell your doctor if you are nursing and monitor infants for diarrhea.
Tell your doctor if you have liver problems.
Please click here for complete Prescribing Information.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
