Predictable relief*
If you have Chronic Constipation, there are probably two things you want most: relief from your symptoms and predictable bowel movements.
AMITIZA may be an option. It is approved to treat Chronic Idiopathic Constipation in adults. In fact, within 24 hours of taking AMITIZA, a majority of people had a bowel movement.* And in clinical studies, patients average 5 to 6 bowel movements a week.† In clinical studies, people experienced relief from symptoms, including the severity of their constipation, as well as abdominal bloating and discomfort.
Individual results may vary.
The most common side effects were nausea, diarrhea, and headache. If nausea occurs, take AMITIZA with food, which may reduce the symptoms of nausea. If your diarrhea or nausea becomes severe, tell your doctor.
These are not all the possible side effects associated with AMITIZA. Your doctor or pharmacist can give you a more complete list of side effects. Talk to your doctor about any side effects you may have after taking AMITIZA.
*In clinical studies, 57% to 63% of patients experienced a bowel movement within 24 hours after taking AMITIZA vs. 32-37% without AMITIZA . Individual results may vary.
†In clinical studies, patients on placebo had an average of 3 to 4 bowel movements per week.
Indication
AMITIZA (24 mcg) twice daily is approved to treat Chronic Idiopathic Constipation in adults. “Idiopathic” means the cause of the constipation is unknown and not due to an underlying illness or medication. AMITIZA (8 mcg) twice daily is approved to treat Irritable Bowel Syndrome with Constipation (IBS-C) in women 18 years of age and older.
Important Safety Information
AMITIZA is not for everyone. If you know or suspect you have a bowel blockage, do not take AMITIZA. If you are unsure, your healthcare provider should evaluate your condition before starting AMITIZA. You should not take AMITIZA if you have severe diarrhea.
AMITIZA has not been studied in pregnant women and should only be used during a pregnancy if the potential benefits justify the potential risk to the fetus. Women should have a negative pregnancy test before beginning treatment with AMITIZA and need to practice effective birth control measures. If you are pregnant or become pregnant while being treated with AMITIZA, talk to your healthcare provider to evaluate the risks to the fetus.
Some patients taking AMITIZA may experience nausea or diarrhea. If nausea occurs, take AMITIZA with food. If your nausea or diarrhea becomes severe, tell your healthcare provider.
Within an hour of taking AMITIZA, a sensation of chest tightness and shortness of breath may occur. These symptoms usually go away within three hours, but may recur with repeated use. Tell your healthcare provider if you experience these symptoms.
The most common side effects of taking AMITIZA (24 mcg) twice daily, orange capsules for Chronic Idiopathic Constipation are nausea, diarrhea, and headache. The most common side effects of taking AMITIZA (8 mcg) twice daily, pink capsules for IBS-C are nausea, diarrhea, and abdominal pain. These are not all the side effects associated with AMITIZA.
Please see complete Prescribing Information.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
