Get predictable relief* from
Chronic Idiopathic Constipation

Ask your doctor about moving to AMITIZA.

If you’re dissatisfied with your current treatment, it may be time for you to try a different treatment for Chronic Idiopathic Constipation—AMITIZA.

Treating your condition with AMITIZA as your doctor prescribes and making lifestyle changes may give you the predictable relief* you want.

AMITIZA 24 mcg twice daily treats Chronic Idiopathic Constipation.

AMITIZA is the only prescription medicine approved by the FDA to treat adults with Chronic Idiopathic Constipation including those over 65. “Idiopathic” simply means the cause of the constipation is not known and not due to an underlying illness or medication.

So if diet, exercise, and over-the-counter medicines haven’t worked, it may be time to ask your doctor if you should move to prescription AMITIZA.

Why move to AMITIZA?

AMITIZA can give ongoing relief† from symptoms of Chronic Constipation, such as abdominal discomfort and bloating
On the first day of taking AMITIZA, a majority of people had a bowel movement*
In clinical studies, people averaged 5 to 6 bowel movements per week‡
AMITIZA is an oral gelcap that you take twice a day with food

Only your doctor will know if AMITIZA is right for you.

*In clinical studies, 57% to 63% of patients experienced a bowel movement within 24 hours after taking AMITIZA vs. 32-37% without AMITIZA. Individual results may vary.
†AMITIZA gave symptom relief of abdominal bloating, abdominal discomfort and constipation severity for 6 to 12 months as demonstrated in clinical safety studies.
‡In clinical studies, patients taking placebo had an average of 3 to 4 bowel movements per week.

** You must meet Eligibility Requirements.

Indication

AMITIZA (24 mcg) twice daily is approved to treat Chronic Idiopathic Constipation in adults. “Idiopathic” means the cause of the constipation is unknown and not due to an underlying illness or medication. AMITIZA (8 mcg) twice daily is approved to treat Irritable Bowel Syndrome with Constipation (IBS-C) in women 18 years of age and older.

Important Safety Information

AMITIZA is not for everyone. If you know or suspect you have a bowel blockage, do not take AMITIZA. If you are unsure, your healthcare provider should evaluate your condition before starting AMITIZA. You should not take AMITIZA if you have severe diarrhea.

AMITIZA has not been studied in pregnant women and should only be used during a pregnancy if the potential benefits justify the potential risk to the fetus. Women should have a negative pregnancy test before beginning treatment with AMITIZA and need to practice effective birth control measures. If you are pregnant or become pregnant while being treated with AMITIZA, talk to your healthcare provider to evaluate the risks to the fetus.

Some patients taking AMITIZA may experience nausea or diarrhea. If nausea occurs, take AMITIZA with food. If your nausea or diarrhea becomes severe, tell your healthcare provider.

Within an hour of taking AMITIZA, a sensation of chest tightness and shortness of breath may occur. These symptoms usually go away within three hours, but may recur with repeated use. Tell your healthcare provider if you experience these symptoms.

The most common side effects of taking AMITIZA (24 mcg) twice daily, orange capsules for Chronic Idiopathic Constipation are nausea, diarrhea, and headache. The most common side effects of taking AMITIZA (8 mcg) twice daily, pink capsules for IBS-C are nausea, diarrhea, and abdominal pain. These are not all the side effects associated with AMITIZA.

Please see complete Prescribing Information.