Pay $0* for AMITIZA
*Subject to maximum benefit. You must meet Eligibility Requirements.
 
3 different conditions
 

AMITIZA is the only prescription
medicine that treats 3 types of chronic constipation

3 different conditions

Did you know there are several different “types” of constipation? AMITIZA is the first and only FDA-approved prescription medicine for the treatment of Chronic Idiopathic Constipation (CIC) in adults, Irritable Bowel Syndrome with Constipation (IBS-C) in adult women, and Constipation caused by Opioids (OIC) in adults with chronic, non-cancer pain. Idiopathic means the cause of constipation is unknown.

AMITIZA Savings Card

The AMITIZA Savings Program is here to help

Join now to get savings and support for managing chronic constipation

Members of the AMITIZA Savings Program can pay $0* every month for AMITIZA prescriptions. Plus, when you sign up, you’ll also get emails full of tips and information to help you manage chronic constipation and support your treatment plan.

*Subject to maximum benefit. You must meet Eligibility Requirements.

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AMITIZA Savings Card

Hear what people are saying

Real people like you are taking AMITIZA for their chronic constipation. In fact, AMITIZA has over 11 million prescriptions written so far. Listen to what patients have to say about their condition, and hear how AMITIZA has helped them.

Individual results may vary.

See what real patients are saying

Get information to support your treatment plan

Real patients

Uses & Important Safety Information

AMITIZA is for CIC in adults, OIC in adults with chronic, non-cancer pain, and IBS-C in women ≥ 18 years. Effectiveness in patients taking methadone has not been established.

Important Safety Information

AMITIZA (lubiprostone) is not for everyone. If you know or suspect you have a bowel blockage, do not take AMITIZA. If you are unsure, your healthcare provider (HCP) should evaluate your condition before starting AMITIZA. You should not take AMITIZA if you have severe diarrhea.

Some patients taking AMITIZA may experience nausea or diarrhea. If nausea occurs, take AMITIZA with food and water, if it becomes severe, tell your HCP. If your diarrhea becomes severe, stop taking AMITIZA and tell your HCP.

Within an hour of taking AMITIZA, a sensation of chest tightness and shortness of breath may occur. These symptoms usually go away within three hours, but may recur with repeated use. Tell your HCP if you experience these symptoms.

The most common side effects of taking AMITIZA (24 mcg) twice daily are nausea, diarrhea, headache, abdominal pain, abdominal distension, and gas for patients treated for CIC; nausea and diarrhea for patients treated for Opioid-Induced Constipation. The most common side effects of taking AMITIZA (8 mcg) twice daily for IBS-C are nausea, diarrhea, and abdominal pain. These are not all the side effects associated with AMITIZA.

Tell your HCP if you are taking a diphenylheptane opioid (e.g. methadone).

AMITIZA has not been studied in pregnant women. Based on animal studies, AMITIZA may cause fetal harm. AMITIZA should only be used during pregnancy if the potential benefits justify the potential risk to the fetus. If you are pregnant or become pregnant while being treated with AMITIZA, talk to your HCP to evaluate the risks to the fetus. Tell your HCP if you are nursing and monitor infants for diarrhea.

Tell your HCP if you have liver problems.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Indication

AMITIZA (lubiprostone) 24 mcg capsules twice daily is approved to treat Chronic Idiopathic Constipation (CIC) in adults. “Idiopathic” means the cause of the constipation is unknown and not due to an underlying illness or medication. AMITIZA 24 mcg twice daily is also approved to treat constipation caused by opioids (OIC), a type of prescription pain medicine, in adults with chronic, non-cancer pain. The effectiveness of AMITIZA has not been established if you are taking a diphenylheptane opioid (e.g., methadone). AMITIZA 8 mcg capsules twice daily is approved to treat Irritable Bowel Syndrome with Constipation (IBS-C) in women 18 years of age and older.

Please click here for complete Prescribing Information.