Real Patients Share Their Experience

Meet Susie, Suzanne, and Miho. Like you, they are all too familiar with the experience of chronic constipation. Watch their videos to hear their stories, and find out how AMITIZA helped. Individual results may vary.

Hear Miho talk about her CIC.
“I'm happy my doctor told me about AMITIZA.”
–Miho, patient with CIC

Individual results may vary.

Get to know these real patients.

Individual results may vary.

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Hear Susie discuss her CIC.

Individual results may vary.

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Hear Suzanne talk about her IBS-C.

Individual results may vary.

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Hear Miho talk about her CIC.

Individual results may vary.

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Get to know these real patients.

Individual results may vary.

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Hear Suzanne talk about her IBS-C.

Individual results may vary.

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Hear Susie discuss her CIC.

Individual results may vary.

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Hear Miho talk about her CIC.

Individual results may vary.

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Video Transcript

MIHO: Hi, I’m Miho. I grew up in Japan and now live in Los Angeles. I’ve never felt comfortable talking about personal issues like chronic constipation.

It’s just so private.

Sometimes I couldn’t go to the bathroom for several days. And when I did go, I felt like I was straining at times.

SUPER: Chronic Idiopathic Constipation may include the following (if experienced for the last 3 months, with symptoms starting at least 6 months ago):

MIHO: So I pretty much kept everything about my chronic constipation to myself. I didn’t talk to my family, my friends, or even my doctor about it.

SUPER: Any 2 or more of the following symptoms: straining, lumpy or hard stools, feeling like your bowel is never completely empty, feeling like your bowel is blocked,...

MIHO: I’ve always been very active. I practice yoga every day, I run, and lately I’ve really gotten into tango dancing and being out on the water. I enjoy getting out and doing activities.

SUPER: ...fewer than 3 bowel movements per week, need to manually pass a bowel movement. And loose stools are rarely present without the use of laxatives.

MIHO: I’ve tried laxatives and other over-the-counter treatments, and they helped. But my symptoms often returned.

SUPER: Once your healthcare provider has a clear understanding of your symptoms, they can give a diagnosis.

MIHO: A couple years ago, I was at a friend’s house and I felt like I had to go to the bathroom.

I had been straining in the bathroom for a while, and my stomach felt uncomfortable.

My friend noticed how long I was gone, so she asked me what was going on and if I needed help.

SUPER: “Idiopathic” means the cause of the constipation is unknown and not due to an underlying illness or medication.

MIHO: That’s when I realized I had been ignoring the signs my body had been giving me. I needed to do something about my chronic constipation. I couldn’t keep it to myself any longer.

I went to my internal medicine doctor, and she was very supportive. She was easy to talk to, and she was willing to listen to my concerns.

When she diagnosed me with chronic idiopathic constipation, it was reassuring…this condition had a name and there were ways that could help treat it.

She told me about AMITIZA, or lubiprostone. She said it wasn’t a laxative or fiber and that it worked differently from them.

SUPER: AMITIZA (lubiprostone) 24 mcg capsules twice daily is approved to treat Chronic Idiopathic Constipation (CIC) in adults.

MIHO: She gave me some samples to take home, and said she had seen it work in some of her other patients with this condition.

I really wanted to try something I hadn’t tried before.

SUPER: Individual results may vary.

MIHO: After taking AMITIZA for a week, I began to see improvements in my bowel frequency.

SUPER: Individual results may vary. In two 4-week clinical studies, people taking AMITIZA averaged 5 to 6 bowel movements per week, versus 3 to 4 without AMITIZA.

MIHO: And after taking it for a few weeks, I told my doctor that I thought AMITIZA was helping to improve my chronic constipation symptoms.

SUPER: Individual results may vary. AMITIZA improves abdominal bloating, abdominal discomfort, stool consistency, straining, and constipation severity associated with CIC.

MIHO: I’m glad I finally talked to my doctor and got a diagnosis and treatment plan that works for me.

SUPER: Individual results may vary. Talk to your healthcare provider to periodically assess the need for continued therapy.

MIHO: I feel like AMITIZA has helped me manage my chronic constipation symptoms.

SUPER: Individual results may vary.

MIHO: What would I say to people who have chronic idiopathic constipation?

Talk to your doctor like I did. Ask if AMITIZA is right for you.

I’m happy my doctor told me about AMITIZA. It’s helped me.

SUPER: Individual results may vary.

VOICEOVER AND SUPER: Indication.
AMITIZA (lubiprostone) 24 microgram capsules twice daily is approved to treat Chronic Idiopathic Constipation (CIC) in adults. “Idiopathic” means the cause of the constipation is unknown and not due to an underlying illness or medication.

Important Safety Information. AMITIZA (lubiprostone) is not for everyone. If you know or suspect you have a bowel blockage, do not take AMITIZA. If you are unsure, your healthcare provider (HCP) should evaluate your condition before starting AMITIZA.

Some patients taking AMITIZA may experience nausea. Take AMITIZA with food and water to reduce the occurrence of nausea.

Do not take AMITIZA if you have severe diarrhea. Some patients taking AMITIZA may experience diarrhea. If your diarrhea becomes severe, stop taking AMITIZA and tell your HCP.

Patients may experience fainting and low blood pressure after taking the first dose or repeated doses of AMITIZA. Stop taking AMITIZA and tell your HCP if these reactions occur. Symptoms usually go away before the next dose but may recur with repeated use. Tell your HCP if you are taking any medications to lower blood pressure. Other side effects such as diarrhea or vomiting may increase the risk of fainting and low blood pressure.

Within an hour of taking AMITIZA, a sensation of chest tightness and shortness of breath may occur. These symptoms usually go away within three hours, but may recur with repeated use. Tell your HCP if you experience these symptoms.

The most common side effects of taking AMITIZA 24 micrograms twice daily for CIC are nausea, diarrhea, headache, abdominal pain, abdominal distension, and gas. These are not all the side effects associated with AMITIZA.

Tell your HCP if you are taking a diphenylheptane opioid (e.g., methadone).

AMITIZA has not been studied in pregnant women. Based on animal studies, AMITIZA may cause fetal harm. AMITIZA should only be used during pregnancy if the potential benefits justify the potential risk to the fetus. If you are pregnant or become pregnant while being treated with AMITIZA, talk to your HCP to evaluate the risks to the fetus. Tell your HCP if you are nursing and monitor infants for diarrhea.

Tell your HCP if you have liver problems.

Please see the accompanying complete Prescribing Information for AMITIZA. The link to the Prescribing Information can be found at the top of this page.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

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Talking to
your doctor

Sharing your history with chronic constipation helps your doctor find the treatment plan that is right for you. The Doctor Discussion Guide can help make the conversation more productive.

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Taking
AMITIZA

Find out what to expect when taking AMITIZA.

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Important Safety
Information

Uses & Important Safety
Information

AMITIZA is used for 3 types of chronic constipation: CIC in adults, OIC in adults with chronic pain that is not caused by active cancer, and IBS-C in women ≥ 18 years. Effectiveness in patients taking methadone has not been established.

Important Safety Information

AMITIZA (lubiprostone) is not for everyone. If you know or suspect you have a bowel blockage, do not take AMITIZA. If you are unsure, your healthcare provider (HCP) should evaluate your condition before starting AMITIZA.

Some patients taking AMITIZA may experience nausea. Take AMITIZA with food and water to reduce the occurrence of nausea.

Do not take AMITIZA if you have severe diarrhea. Some patients taking AMITIZA may experience diarrhea. If your diarrhea becomes severe, stop taking AMITIZA and tell your HCP.

Patients may experience fainting and low blood pressure after taking the first dose or repeated doses of AMITIZA. Stop taking AMITIZA and tell your HCP if these reactions occur. Symptoms usually go away before the next dose but may recur with repeated use. Tell your HCP if you are taking any medications to lower blood pressure. Other side effects such as diarrhea or vomiting may increase the risk of fainting and low blood pressure.

Within an hour of taking AMITIZA, a sensation of chest tightness and shortness of breath may occur. These symptoms usually go away within three hours, but may recur with repeated use. Tell your HCP if you experience these symptoms.

The most common side effects of taking AMITIZA 24 mcg twice daily for CIC are nausea, diarrhea, headache, abdominal pain, abdominal distension, and gas. The most common side effects of taking AMITIZA 24 mcg twice daily for Opioid-Induced Constipation are nausea and diarrhea. The most common side effects of taking AMITIZA 8 mcg twice daily for IBS-C are nausea, diarrhea, and abdominal pain. These are not all the side effects associated with AMITIZA.

Tell your HCP if you are taking a diphenylheptane opioid (e.g., methadone).

AMITIZA has not been studied in pregnant women. Based on animal studies, AMITIZA may cause fetal harm. AMITIZA should only be used during pregnancy if the potential benefits justify the potential risk to the fetus. If you are pregnant or become pregnant while being treated with AMITIZA, talk to your HCP to evaluate the risks to the fetus. Tell your HCP if you are nursing and monitor infants for diarrhea.

Tell your HCP if you have liver problems.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Indications

AMITIZA (lubiprostone) 24 mcg capsules twice daily is approved to treat Chronic Idiopathic Constipation (CIC) in adults. “Idiopathic” means the cause of the constipation is unknown and not due to an underlying illness or medication. AMITIZA 24 mcg twice daily is also approved to treat constipation caused by opioids, a type of prescription pain medicine, in adults with chronic pain that is not caused by active cancer. The effectiveness of AMITIZA has not been established if you are taking a diphenylheptane opioid (e.g., methadone). AMITIZA 8 mcg capsules twice daily is approved to treat Irritable Bowel Syndrome with Constipation (IBS-C) in women ≥ 18 years of age.

Please click here for complete Prescribing Information.