Real Patients Share Their Experience

Meet Susie, Suzanne, and Miho. Like you, they are all too familiar with the experience of chronic constipation. Watch their videos to hear their stories, and find out how AMITIZA helped. Individual results may vary.

Individual results may vary.

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Get to know these real patients.

Get to know these real patients.

Individual results may vary.

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Hear Susie discuss her CIC.

Individual results may vary.

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Hear Suzanne talk about her IBS-C.

Hear Suzanne talk about her IBS-C.

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Hear Miho talk about her CIC.

Hear Miho talk about her CIC.

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Video Transcript

SUSIE: Hi, I’m Susie. I feel like I have been dealing with chronic constipation for a very long time. It’s hard to remember a time in my adult life when I didn’t feel like I was dealing with constipation. I’ve always been pretty active.

SUPER: Chronic Idiopathic Constipation may include the following (if experienced for the last 3 months, with symptoms starting at least 6 months ago):

SUSIE: In addition to my job in a medical office, I’ve always loved hiking, gardening, and volunteering in my community.

SUPER: Any 2 or more of the following symptoms: straining, lumpy or hard stools, feeling like your bowel is never completely empty, feeling like your bowel is blocked,...

SUSIE: Sometimes, I would get this “full, bloated” feeling. And 3 or more days within a week without going was not uncommon for me.

SUPER: ...fewer than 3 bowel movements per week, need to manually pass a bowel movement. And loose stools are rarely present without the use of laxatives.

SUSIE: When I tried to go I often had to strain. After several days like that, I’d have to resort to over-the-counter fiber, enemas, and other types of laxatives.

SUPER: Once your healthcare provider has a clear understanding of your symptoms, they can give a diagnosis.

SUSIE: Sometimes I even had to take them with me to help me.

SUPER: “Idiopathic” means the cause of the constipation is unknown and not due to an underlying illness or medication.

SUSIE: I thought maybe I wasn’t drinking enough water, so my husband, Alan, would do his best to make sure that I did.

He would even call me whenever I had days between bowel movements, just to remind me to drink water.

I’ve tried many other things to get some relief. Laxatives, stool softeners, fiber…but they were not enough. And Alan would help me keep track of what I was eating. He even helped me track my bowel movements.

He’s always been that way—making sure I would keep up with all the details and tracking.

We were trying so hard. But no matter what we did, my chronic constipation symptoms kept returning.

I kept telling Alan, “I really need to do something about my constipation. I can’t keep doing this.”

Alan said, “I think it’s time to talk to a specialist.”

I was pleased when I was referred to a gastroenterologist. He looked at my medical history, symptoms that Alan and I had tracked, and he diagnosed me with chronic idiopathic constipation.

I couldn’t believe it. After all this time, my condition finally had a name.

The gastroenterologist also said that a prescription medicine called AMITIZA, or lubiprostone, might be able to help me.

He said it works different from all the laxatives and fiber that I’d tried before.

SUPER: AMITIZA (lubiprostone) 24 mcg capsules twice daily is approved to treat Chronic Idiopathic Constipation (CIC) in adults.

SUSIE: So I gave AMITIZA a try, and you know what? After a week or so, I began to see improvement in my bowel movements.

SUPER: Individual results may vary. In two 4-week clinical studies, people taking AMITIZA averaged 5 to 6 bowel movements per week, versus 3 to 4 without AMITIZA.

SUSIE: I was going to the bathroom more often, and I wasn’t straining as much.

AMITIZA really worked for me. I called the people who knew about my condition just to tell them.

SUPER: Individual results may vary. AMITIZA improves abdominal bloating, abdominal discomfort, stool consistency, straining, and constipation severity associated with CIC.

SUSIE: I would tell anyone who might be dealing with chronic constipation symptoms to go talk to your doctor, get a diagnosis and ask if AMITIZA might be an option for you.

SUPER: Individual results may vary. The need for continued therapy should be periodically assessed with your healthcare provider.

SUSIE: I have a treatment that works for me and Alan doesn’t worry about my symptoms as much.

SUPER: Individual results may vary.

SUSIE: I am a believer in AMITIZA.

SUPER: Individual results may vary.

VOICEOVER AND SUPER: Indication. AMITIZA (lubiprostone) 24 microgram capsules twice daily is approved to treat Chronic Idiopathic Constipation (CIC) in adults. “Idiopathic” means the cause of the constipation is unknown and not due to an underlying illness or medication.

Important Safety Information. AMITIZA (lubiprostone) is not for everyone. If you know or suspect you have a bowel blockage, do not take AMITIZA. If you are unsure, your healthcare provider (HCP) should evaluate your condition before starting AMITIZA.

Some patients taking AMITIZA may experience nausea. Take AMITIZA with food and water to reduce the occurrence of nausea.

Do not take AMITIZA if you have severe diarrhea. Some patients taking AMITIZA may experience diarrhea. If your diarrhea becomes severe, stop taking AMITIZA and tell your HCP.

Patients may experience fainting and low blood pressure after taking the first dose or repeated doses of AMITIZA. Stop taking AMITIZA and tell your HCP if these reactions occur. Symptoms usually go away before the next dose but may recur with repeated use. Tell your HCP if you are taking any medications to lower blood pressure. Other side effects such as diarrhea or vomiting may increase the risk of fainting and low blood pressure.

Within an hour of taking AMITIZA, a sensation of chest tightness and shortness of breath may occur. These symptoms usually go away within three hours, but may recur with repeated use. Tell your HCP if you experience these symptoms.

The most common side effects of taking AMITIZA 24 micrograms twice daily for CIC are nausea, diarrhea, headache, abdominal pain, abdominal distension, and gas. These are not all the side effects associated with AMITIZA.

Tell your HCP if you are taking a diphenylheptane opioid (e.g., methadone).

AMITIZA has not been studied in pregnant women. Based on animal studies, AMITIZA may cause fetal harm. AMITIZA should only be used during pregnancy if the potential benefits justify the potential risk to the fetus. If you are pregnant or become pregnant while being treated with AMITIZA, talk to your HCP to evaluate the risks to the fetus. Tell your HCP if you are nursing and monitor infants for diarrhea.

Tell your HCP if you have liver problems.

Please see the accompanying complete Prescribing Information for AMITIZA. The link to the Prescribing Information can be found at the top of this page.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

 

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Talking to your doctor

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Taking AMITIZA

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Uses & Important Safety Information

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AMITIZA is used for 3 types of chronic constipation: CIC in adults, OIC in adults with chronic pain that is not caused by active cancer, and IBS-C in women ≥ 18 years. Effectiveness in patients taking methadone has not been established.

Important Safety Information

AMITIZA (lubiprostone) is not for everyone. If you know or suspect you have a bowel blockage, do not take AMITIZA. If you are unsure, your healthcare provider (HCP) should evaluate your condition before starting AMITIZA.

Some patients taking AMITIZA may experience nausea. Take AMITIZA with food and water to reduce the occurrence of nausea.

Do not take AMITIZA if you have severe diarrhea. Some patients taking AMITIZA may experience diarrhea. If your diarrhea becomes severe, stop taking AMITIZA and tell your HCP.

Patients may experience fainting and low blood pressure after taking the first dose or repeated doses of AMITIZA. Stop taking AMITIZA and tell your HCP if these reactions occur. Symptoms usually go away before the next dose but may recur with repeated use. Tell your HCP if you are taking any medications to lower blood pressure. Other side effects such as diarrhea or vomiting may increase the risk of fainting and low blood pressure.

Within an hour of taking AMITIZA, a sensation of chest tightness and shortness of breath may occur. These symptoms usually go away within three hours, but may recur with repeated use. Tell your HCP if you experience these symptoms.

The most common side effects of taking AMITIZA 24 mcg twice daily for CIC are nausea, diarrhea, headache, abdominal pain, abdominal distension, and gas. The most common side effects of taking AMITIZA 24 mcg twice daily for Opioid-Induced Constipation are nausea and diarrhea. The most common side effects of taking AMITIZA 8 mcg twice daily for IBS-C are nausea, diarrhea, and abdominal pain. These are not all the side effects associated with AMITIZA.

Tell your HCP if you are taking a diphenylheptane opioid (e.g., methadone).

AMITIZA has not been studied in pregnant women. Based on animal studies, AMITIZA may cause fetal harm. AMITIZA should only be used during pregnancy if the potential benefits justify the potential risk to the fetus. If you are pregnant or become pregnant while being treated with AMITIZA, talk to your HCP to evaluate the risks to the fetus. Tell your HCP if you are nursing and monitor infants for diarrhea.

Tell your HCP if you have liver problems.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Indications

AMITIZA (lubiprostone) 24 mcg capsules twice daily is approved to treat Chronic Idiopathic Constipation (CIC) in adults. “Idiopathic” means the cause of the constipation is unknown and not due to an underlying illness or medication. AMITIZA 24 mcg twice daily is also approved to treat constipation caused by opioids, a type of prescription pain medicine, in adults with chronic pain that is not caused by active cancer. The effectiveness of AMITIZA has not been established if you are taking a diphenylheptane opioid (e.g., methadone). AMITIZA 8 mcg capsules twice daily is approved to treat Irritable Bowel Syndrome with Constipation (IBS-C) in women ≥ 18 years of age.

Please click here for complete Prescribing Information.

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